Migraine

It is thought that Anti-Wrinkle Injections may inhibit the release of peripheral nociceptive neurotransmitters, which may then have a knock-on effect on the central pain processing systems that generate migraine headaches.

In other words, the injections help by blocking the sensory nerves in the head. (Anti-Wrinkle Injections has been shown to reduce pain in cervical dystonia, neuropathic pain, lower back pain, spasticity, myofascial pain, and bladder pain.)

When used to treat migraines, the headaches should lessen in frequency and severity over one to two weeks, with the effect lasting up to 4 months. The success rate can be as high as 65% in certain populations, and can be repeated every three to four months.

Botulinium Toxin was licensed specifically for the treatment of chronic migraine in July 2010 by the Medicines and Healthcare products Regulatory Agency (MHRA). Clinical trials leading to the approval of OnaAnti-Wrinkle Injections A were called PHASE III Research Evaluating Migraine Prophylaxis Therapy (PREEMPT) protocol. This is a slightly different approach to treatment than for cosmetic reasons.

With this protocol, developed and tested extensively, small injections of multiple units each are placed at prescribed locations just under the skin over the forehead, sides of the head, and back of the head and neck.